Clinker: visualizing fusion genes detected in RNA-seq data
نویسندگان
چکیده
منابع مشابه
FusionCancer: a database of cancer fusion genes derived from RNA-seq data
BACKGROUND Fusion genes are chimeric results originated from previous separate genes with aberrant functions. The resulting protein products may lead to abnormal status of expression levels, functions and action sites, which in return may cause the abnormal proliferation of cells and cancer development. RESULTS With the emergence of next-generation sequencing technology, RNA-seq has spurred g...
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Gene fusion events and other types of chromosomal translocations are known to be related to several types of cancers and can be interpreted as hallmarks for the corresponding development stage of the disease. Therefore the detection of these translocations is attracting interest in modern genomics [1]. RNA-seq technology has achieved an unprecedented throughput and resolution which makes it one...
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ژورنال
عنوان ژورنال: GigaScience
سال: 2018
ISSN: 2047-217X
DOI: 10.1093/gigascience/giy079